(s)-(-)-2-(1-hydroxyethyl)pyridine
The compound (S)-(-)-2-(1-hydroxyethyl)pyridine is a chiral molecule that contains a pyridine ring with a 1-hydroxyethyl substituent at the 2-position. The (S) configuration indicates the stereochemistry of the chiral center, which is the carbon bearing the hydroxyl group (OH) and the ethyl group (CH₃-CH-).
Structure:
- Pyridine ring: A six-membered aromatic ring with one nitrogen atom.
- 2-position substituent: A 1-hydroxyethyl group (–CH(OH)CH₃) attached to the pyridine ring at the 2-position.
- Chirality: The carbon in the 1-hydroxyethyl group is chiral, and the (S) configuration specifies the spatial arrangement of the substituents around this carbon.
Key Features:
- Chiral center: The carbon bearing the OH and CH₃ groups is stereogenic.
- Optical activity: The compound is optically active due to the chiral center, and the (–) sign indicates that it rotates plane-polarized light to the left (levorotatory).
- Stereochemistry: The (S) configuration is assigned based on the Cahn-Ingold-Prelog priority rules.
Applications:
- This type of compound is often used in asymmetric synthesis, coordination chemistry, or as a ligand in catalysis.
- It may also serve as a building block for pharmaceuticals or agrochemicals due to the presence of both a pyridine ring and a chiral alcohol.
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