(R)-()-2-chloro-1-phenylethyl alcohol

2025年1月3日
产品资讯

(R)-()-2-chloro-1-phenylethyl alcohol

(R)-(+)-2-Chloro-1-phenylethyl alcohol is a chiral organic compound with the following structure:

  • Molecular Formula: C₈H₉ClO
  • Structure:
     Cl
      |
  Ph-CH-CH₂OH
  • Ph: Phenyl group (C₆H₅)
  • Cl: Chlorine atom
  • CH₂OH: Hydroxymethyl group

Key Features:

  1. Chirality: The compound has a chiral center at the carbon bearing the chlorine atom (C2), making it optically active.
  2. Stereochemistry: The (R) configuration indicates the spatial arrangement of substituents around the chiral center according to the Cahn-Ingold-Prelog priority rules.
  3. Optical Activity: The (+) sign indicates that the compound is dextrorotatory, meaning it rotates plane-polarized light to the right.

Synthesis:

This compound can be synthesized via asymmetric reduction or chiral resolution methods. One common approach involves the reduction of 2-chloro-1-phenylethanone (a ketone) using a chiral reducing agent or catalyst to ensure the formation of the (R)-enantiomer.

Applications:

  • Chiral Building Block: Used in organic synthesis to create more complex chiral molecules.
  • Pharmaceuticals: May serve as an intermediate in the synthesis of chiral drugs.
  • Asymmetric Catalysis: Can be used in studies of enantioselective reactions.

Properties:

  • Boiling Point: Varies depending on the purity and solvent.
  • Solubility: Likely soluble in organic solvents like ethanol, methanol, and dichloromethane.
  • Optical Rotation: The specific rotation ([α]₀) will depend on the solvent and concentration.

If you need further details about its synthesis, reactions, or applications, feel free to ask!

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