(R)-(-)-2-Butanol

2025年1月3日
产品资讯

(R)-(-)-2-Butanol

(R)-(-)-2-Butanol is a chiral alcohol with the molecular formula C₄H₁₀O. It is one of the two enantiomers of 2-butanol, the other being (S)-(+)-2-butanol. The (R)-(-)-2-butanol enantiomer has a specific rotation that is negative, indicating that it rotates plane-polarized light to the left (levorotatory).

Key Features:

  • Chemical Structure:
     CH₃
      |
  H₃C-C*-OH
      |
     CH₂CH₃

The asterisk (*) denotes the chiral center.

  • Chirality: The (R)-(-)-2-butanol has the R-configuration at the chiral center, meaning that the groups around the chiral center are arranged in a specific order according to the Cahn-Ingold-Prelog priority rules.
  • Optical Activity: It is levorotatory, meaning it rotates plane-polarized light to the left (counterclockwise).
  • Physical Properties:
  • Boiling point: ~99-100°C
  • Density: ~0.81 g/cm³
  • Solubility: Miscible with water and many organic solvents.

Uses:

  • Chemical Synthesis: (R)-(-)-2-Butanol is used as a chiral building block in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and fine chemicals.
  • Solvent: It can be used as a solvent in various chemical reactions.
  • Chiral Resolutions: It is sometimes used in the resolution of racemic mixtures.

Safety:

  • Handling: It is flammable and should be handled with care, avoiding exposure to open flames or high temperatures.
  • Toxicity: It is generally considered to have low toxicity, but as with all chemicals, appropriate safety precautions should be taken, including the use of personal protective equipment (PPE).

This enantiomer is important in fields that require chiral specificity, such as asymmetric synthesis and the study of stereochemistry.

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