Pulegone
Pulegone is a naturally occurring organic compound classified as a monoterpene ketone. It is found in various plants, particularly in the mint family (Lamiaceae), such as pennyroyal (Mentha pulegium) and catmint (Nepeta cataria). Pulegone is known for its minty aroma and is used in the flavoring and fragrance industries.
Key Characteristics:
- Chemical Formula: C10H16O
- Molecular Weight: 152.23 g/mol
- Appearance: Colorless to pale yellow liquid
- Odor: Minty, camphoraceous
Uses:
- Flavoring Agent: Pulegone is used to impart a minty flavor to foods, beverages, and oral care products.
- Fragrance: It is used in perfumes and scented products for its refreshing aroma.
- Traditional Medicine: Historically, pennyroyal oil, which contains pulegone, has been used in traditional medicine for its purported medicinal properties, though its use is now limited due to toxicity concerns.
Toxicity and Safety:
Pulegone is considered toxic if ingested in large quantities. It has been associated with liver and lung damage, and in severe cases, it can be fatal. The compound is metabolized in the liver to form reactive intermediates that can cause cellular damage. Due to its toxicity, the use of pulegone in food and consumer products is regulated in many countries.
Regulation:
- FDA: The U.S. Food and Drug Administration (FDA) has restricted the use of pulegone in food products.
- EFSA: The European Food Safety Authority (EFSA) has also set limits on the concentration of pulegone in food and beverages to ensure consumer safety.
Research:
Research on pulegone has focused on its toxicological profile, metabolism, and potential therapeutic uses. Studies have explored its effects on the liver, its carcinogenic potential, and its role in traditional medicine. However, due to its toxicity, its therapeutic use is limited and not widely accepted in modern medicine.
Conclusion:
While pulegone is a valuable compound in the flavor and fragrance industries, its toxicity necessitates careful regulation and handling. Its use in consumer products is limited to ensure safety, and ongoing research continues to explore its effects and potential applications.
中国|杭州|桐庐|蜂竞生物fenjinbio.com | 联系：17767155726，E-mail:hwl5726@163.com