Oral rinse formulation cooling agent
When formulating an oral rinse, cooling agents are added to provide a refreshing sensation. Common cooling agents used in oral care products include:
1. Menthol
- A widely used cooling agent derived from mint oils.
- Provides a strong, refreshing cooling effect.
- Typical concentration: 0.01% to 0.1%.
2. Eucalyptol
- Derived from eucalyptus oil.
- Offers a mild cooling sensation and has antimicrobial properties.
- Typical concentration: 0.01% to 0.1%.
3. Camphor
- Provides a cooling and soothing effect.
- Often used in combination with menthol for enhanced cooling.
- Typical concentration: 0.01% to 0.1%.
4. Menthyl Lactate
- A synthetic cooling agent derived from menthol.
- Provides a long-lasting cooling sensation without the strong odor of menthol.
- Typical concentration: 0.05% to 0.2%.
5. WS-3 (Ethyl Menthane Carboxamide)
- A synthetic cooling agent with a potent and long-lasting cooling effect.
- Often used in combination with other cooling agents.
- Typical concentration: 0.01% to 0.05%.
6. WS-23 (Isopulegol Derivative)
- Another synthetic cooling agent with a clean, refreshing effect.
- Works well in low concentrations.
- Typical concentration: 0.01% to 0.05%.
7. Peppermint Oil
- A natural oil that provides a cooling and refreshing sensation.
- Contains menthol as its active cooling component.
- Typical concentration: 0.05% to 0.2%.
8. Spearmint Oil
- Provides a milder cooling effect compared to peppermint oil.
- Often used for a more subtle flavor and cooling sensation.
- Typical concentration: 0.05% to 0.2%.
9. Coolact® (Menthoxypropanediol)
- A synthetic cooling agent with a smooth and refreshing effect.
- Often used in combination with other cooling agents.
- Typical concentration: 0.05% to 0.2%.
10. Icilin
- A potent synthetic cooling agent that activates cold-sensitive receptors.
- Provides an intense cooling sensation at very low concentrations.
- Typical concentration: 0.001% to 0.01%.
Considerations for Formulation:
- Flavor Compatibility: Ensure the cooling agent complements the overall flavor profile of the oral rinse.
- Sensory Experience: Balance the cooling intensity to avoid overwhelming the user.
- Safety and Regulatory Compliance: Ensure all ingredients are approved for oral use and comply with local regulations.
- Stability: Test the formulation to ensure the cooling agent remains effective over the product’s shelf life.
Example Formulation:
- Base: Water, alcohol (optional), humectants (e.g., glycerin or sorbitol).
- Cooling Agents: Menthol (0.05%), WS-3 (0.02%).
- Flavoring: Peppermint oil (0.1%).
- Preservatives: Sodium benzoate, potassium sorbate.
- Sweeteners: Sodium saccharin, xylitol.
- Surfactants: Poloxamer 407 (optional, for foaming).
Always conduct stability and safety testing to ensure the final product meets quality standards.
FJ081-Rinse cooling agent|漱口水用凉感剂|蜂竞生物fenjinbio.com| 联系：17767155726，E-mail:hwl5726@163.com