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Menthyl Succinate, also known as Monomethyl Succinate or (-)-Menthyl Succinate, is a chemical compound with the CAS number 77341-67-4. Below is a detailed overview of its properties, uses, and related information based on the search results:
1. Chemical Properties
- Molecular Formula: C₁₄H₂₄O₄ .
- Molecular Weight: 256.34 g/mol .
- Appearance: White to off-white crystalline powder or solid .
- Density: 1.1±0.1 g/cm³ .
- Boiling Point: 374.3±25.0 °C at 760 mmHg .
- Flash Point: 132.3±16.7 °C .
- Melting Point: Not specified (N/A) .
- Solubility: Soluble in methanol .
- Refractive Index: 1.478 .
2. Uses and Applications
- Cosmetics: Used as an astringent and fragrance functional ingredient in cosmetic products. It helps tighten the skin and is a component of perfume oils .
- Chemical Reagent: Employed in the synthesis of fine chemicals, pharmaceutical intermediates, and material intermediates .
- Research: Studied for its potential pro-heating and anti-pathogenic properties in skin chronic wounds .
3. Safety and Handling
- Hazard Information: Classified as hazardous due to its potential to cause severe eye irritation (GHS classification) .
- Precautions:
- Wear protective gloves, goggles, and masks when handling.
- Avoid contact with skin, eyes, and clothing.
- Use in well-ventilated areas .
- First Aid Measures:
- Eye Contact: Rinse with water for several minutes and seek medical attention.
- Skin Contact: Wash with soap and water.
- Inhalation: Move to fresh air and seek medical help .
4. Storage and Packaging
- Storage Conditions: Store in a cool, dry place, away from incompatible materials like oxidizers. Keep containers tightly closed .
- Packaging: Available in 25 kg paper drums or 1 kg aluminum foil bags for light-sensitive storage .
5. Synonyms and Related Compounds
- Synonyms:
- (-)-Menthyl Succinate
- 4-{[(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl]oxy}-4-oxobutanoic acid
- Monomethyl Succinate .
- Related Compounds:
- (+)-Bis(d-Menthyl) Succinate (CAS: 96149-05-2)
- (-)-Bis(l-Menthyl) Succinate (CAS: 34212-59-4) .
6. Regulatory and Commercial Information
- CAS Number: 77341-67-4 .
- EINECS Number: 426-890-4 .
- Purity: ≥98% (GC&T) .
- Regulatory Compliance: Meets USP/EP standards for export .
7. Ecological and Toxicological Data
- Ecotoxicity: No specific data available .
- Toxicity: No acute toxicity data reported, but it is classified as an eye irritant .
8. Additional Notes
- Menthyl Succinate is derived from menthol and succinic acid, combining cooling properties with chemical functionality .
- It is used in both industrial and cosmetic applications, highlighting its versatility .
For further details, you can refer to the original sources: Fenjin Bio .