(S)-()-1,3-Butanediol
(S)-(+)-1,3-Butanediol is a chiral diol with the molecular formula C₄H₁₀O₂. It is one of the two enantiomers of 1,3-butanediol, with the (S)-configuration at the chiral center. Here are some key points about this compound:
- Structure:
- The molecule has a hydroxyl group (-OH) on the first and third carbon atoms.
- The chiral center is at the second carbon (C2), where the (S)-configuration indicates the spatial arrangement of the substituents around this carbon.
- Optical Activity:
- The “(+)” in the name indicates that this enantiomer is dextrorotatory, meaning it rotates plane-polarized light to the right (clockwise).
- Uses:
- Chemical Synthesis: It is used as a building block in organic synthesis, particularly in the production of chiral compounds.
- Pharmaceuticals: It can serve as an intermediate in the synthesis of various drugs and bioactive molecules.
- Solvent: It is sometimes used as a solvent or co-solvent in chemical reactions.
- Cosmetics: It may be used in cosmetic formulations due to its moisturizing properties.
- Physical Properties:
- Appearance: Typically a colorless liquid.
- Boiling Point: Around 207-208°C.
- Solubility: Soluble in water and many organic solvents.
- Synthesis:
- It can be synthesized through various methods, including the reduction of corresponding hydroxy ketones or through asymmetric synthesis techniques to obtain the desired (S)-enantiomer.
- Safety:
- As with many chemical compounds, appropriate safety precautions should be taken when handling (S)-(+)-1,3-butanediol, including the use of personal protective equipment (PPE) and proper ventilation.
This compound is of particular interest in fields requiring chiral specificity, such as asymmetric synthesis and the development of enantiomerically pure pharmaceuticals.
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